A 16 year old with Blurred Vision
Digital Journal of Ophthalmology 2003
Volume 9, Number 4
December 29, 2003
- A 16 year old girl presented with gradually decreasing vision OS for a duration of 12 months.
Past ocular history:
- Iris coloboma OD
- Retinochoroidal colobomas OD & OS
Medical & Family history:
|Visual acuity: |
OD 20/60 OS 20/60
OD: Inferonasal iris coloboma (Figure 1)
OD: Extensive inferior chorioretinal coloboma (Figure 2)
OS: Partial inferior chorioretinal coloboma (Figure 3), optic disc pit (Figure 3), and extensive serous elevation of the macula (Figure 4)
Applanation tonometry: Normal (OU)
Inferonasal Iris Coloboma OD
Extensive Inferior Retinochoroidal Coloboma OD
Optic Disc Pit with Partial Inferior Retinochoroidal Coloboma OS
Fundus Fluorescein Angiogram demonstrating central serous retinopathy
| The patient had pars plana vitrectomy, intraocular gas injection (SF6)|
and laser photocoagulation to the left eye. She was followed up for a
period of 12 months. There has been no improvement in the visual
acuity but the retina remains flat in the operated eye.
|1. Central serous retinopathy secondary to optic disc pit|
2. Macular or paramacular hole
3. Peripheral retinal detachment with pooling of subretinal fluid in the macula
4. Peripheral chorioretinal lesions leading to exudative detachment extending into the macular area.
|Diagnosis and Discussion|
|Congenital optic disc pit is a rare developmental defect and is a craterlike indentation on the surface of the optic disc. It is usually unilateral and is found in the temporal part of the optic nerve head. It varies in size and depth. The age at presentation varies from infancy to the seventh decade and there is no sex predeliction (1). Most pits are non-familial although autosomal dominant inheritance has been reported in a few (2). Various theories regarding formation of optic disc pits exist. Some think that anomalous development of the primordial optic nerve is responsible while others postulate incomplete closure of the embryonic fissure (3). Congenital optic disc pits are associated with iris, optic disc and chorioretinal colobomas (1,2). In the renal coloboma syndrome posterior colobomas are associated with optic disc pits and early renal failure making it essential to do simple nephrological tests to rule out renal involvement in such patients (4).|
In 30-40% of the cases of congenital optic disc pits, there is a serous elevation of the macula resulting in reduced visual acuity (5,6). The pathogenesis of this is unclear. The subretinal fluid could be derived from the vitreous or the cerebrospinal fluid in the subarachnoid space around the optic disc. Other macular lesions that can be seen include macular edema, macular hole, macular cyst and pigmentary mottling.
Spontaneous reattachment of the retina has been reported but is rare(1). Macular detachment is associated with a very poor visual prognosis. Any treatment that allows the sensory retina to reattach is desirable in comparison to allowing the detachment to follow its natural course. The various treatment modalities include ocular patching and mannitol, bed rest, steroids, photocoagulation, diathermy, cryotherapy, drainage of subretinal fluid, scleral buckling procedures and intraocular gas injection. The above treatments have variable results and the best treatment has not been determined. The following treatment plan has been recommended (7): If there is no permanent macular damage, observation is advised for 3 months. If spontaneous reattachment occurs, the patient can proceed for laser treatment. If there is no reattachment bed rest and semi pressure eye patching for 2 days followed by laser and observation for 2 months is suggested. Further failure to reattach can be treated with intraocular gas and laser. If failure to reattach persists, vitrectomy with air/fluid exchange and additional laser is recommended.
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