Elise Torczynski, MD | University of Illinois Eye and Ear Infirmary, Chicago IL Howard H. Tessler, MD | University of Illinois Eye and Ear Infirmary, Chicago IL Debra Goldstein, MD | University of Illinois Eye and Ear Infirmary, Chicago IL Teresa C. Chen, MD | Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA
The differential diagnosis of hypopyon uveitis can be grouped INTO several categories. Infectious etiologies include hypopyon associated with corneal ulcers or endophthalmitis. Severe acute iridocyclitis can also present as hypopyon uveitis. Certain systemic drugs can also cause hypopyon uveitis as well (e.g. rifabutin) Pseudo-hypopyons can be seen with accidental intraocular steroid injections as well as ghost-cell glaucoma. Hypopyons can not only be seen with retained intraocular foreign bodies, including toxic lens syndrome, but also occurs after trauma. Surgical causes of hypopyons include refractive surgery as well as pars plana vitrectomy with silicone oil injection. Necrosis of intraocular tumors or metastases (e.g. leukemia, non-Hodgkins lymphoma, and retinoblastoma) can also cause a hypopyon uveitis.