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A 30 year old woman with gradual vision loss OU
Digital Journal of Ophthalmology 2005
Volume 11, Number 15
August 15, 2005
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Darren J. Bell | University of Tennessee
Joseph Mastellone | University of Tennessee
Edward Chaum MD PhD | Univ. of Tennessee Memphis
Differential Diagnosis
The literature on the epidemiology of diabetic retinopathy demonstrates a generally slow progression of nonproliferative diabetic retinopathy (NPDR) and preproliferative disease to the development of proliferative diabetic retinopathy (PDR) in diabetic patients (1). This patient with newly diagnosed chronic myelogenous leukemia (CML) progressed from NPDR to bilateral PDR with high-risk characteristics (HRC) over a period of 3 months. Possible contributing factors and reasons for progression include atypically rapid progression of underlying diabetic retinopathy, other factors such as hypertension or anemia, or rapid progression due to the leukemia.